Protective effects of Zygophyllum album extract against deltamethrin-induced hyperglycemia and hepato-pancreatic disorders in rats

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چکیده

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Protective effects of Zygophyllum album extract against deltamethrin-induced hyperglycemia and hepato-pancreatic disorders in rats.

The current study was designed to investigate the possible mechanism involved in hyperglycemia induced by chronic exposure to deltamethrin (DLM) in rat and to assess whether this damage is amenable to modulation by Zygophyllum album. DLM, a synthetic pyrethroid pesticide, was administrated at a dose of 4 mg/kg body mass, during 60 days. Compared with control, DLM showed a significant increase o...

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Antioxidant and Protective Effects of Plant Extract against Deltamethrin-induced Oxidative Stress in Liver and Kidney – A Review

Deltamethrin is one of the most commonly used Pyrethroid around the world. Oxidative stress is one of the most deltamethrin toxicity mechanisms. According to many studies, it has been shown that the liver, due to its role, is the main source of accumulation of high concentrations of deltamethrin metabolites. Also the kidney plays a very important role in regulating homeostasis of the body and r...

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Protective effects of rosuvastatin against hyperglycemia-induced oxidative damage in the pancreas of streptozotocin-induced diabetic rats

Introduction: According to the powerful antioxidant effects of rosuvastatin, the present study aimed to examine the protective effects of rosuvastatin against oxidative damage of diabetic pancreas by potentiation of the antioxidant capacity in streptozotocin-induced diabetic rats. Methods: Experiment was performed in four groups of male Wistar rats (n=6 in each group): normal, diabetic and ...

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Appraisal the Protective Effects of Cymbopogon Schoenanthus Extract against Reproductive Disorders and Carcinogenic Effects of Formalin in Experimental Male Rats

Formaldehyde has been documented to be naturally present in many common foods. There has been a big public concern over the use of formaldehyde in the preservation of food. Also, it is commonly used as a chemical substance, usually in the life and can interact with many bio-substance in the human body. The present study target to investigate the protective effects of  Cymbopogon schoenanthus (C...

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ژورنال

عنوان ژورنال: Canadian Journal of Physiology and Pharmacology

سال: 2016

ISSN: 0008-4212,1205-7541

DOI: 10.1139/cjpp-2016-0132